Everyone wants to look young, beautiful, and, of course, live a happy, healthy, and long life. Researchers in New York investigated demographics from more than 40 countries and found out that a possible increase in life expectancy had already been reached in the 1990s. Today, the oldest (still-living) person in the world is about 115 years old. However, life expectancy continues to increase as medical care, nutrition, and living conditions are improving rapidly. In other words, more people are reaching a respectable age these days, but those who live extremely long no longer survive as long as approximately 120 years. It is possible that people will live a little longer (up to 115 years), but the chances of someone in the world surviving to 125 are very little. All of this can, of course, be replaced by some major medical or technological breakthrough. Researchers try to find out more about longevity and secrets of healthy and long life. The medical advances of the last few decades have extended life expectancy and improved quality of life. We are living in a world full of information, so everyone should know about longevity startups. In this article, we are going to look closer at 5 longevity startups.
Juvenescence is a new innovative biotech longevity company and united group of scientists, making great advances in society and helping people to live long and happy lives including healthy aging. Juvenescence company is oriented in production of Ketone supplements. Low-carbohydrate and ketogenic diets have several benefits for health and metabolism. Choosing healthy foods and supplements will help maximize the diet’s benefits. The ketogenic diet, or keto diet, has been under consideration for over 30 years. Numerous studies have been published during this period demonstrating the benefits of such a diet in the treatment of a variety of health conditions, including obesity / overweight. One of the main distinguishing features of a ketogenic diet is a high-fat, low-carbohydrate diet. The name of this diet is associated with the energy-producing molecules produced by our body – ketones. Ketones are produced in the liver, and their production begins when the body’s glucose stores begin to follow (as fat intake increases). In the liver, fat is converted into ketones, which provide energy to the body and brain. In a ketogenic diet, we get 70% of our energy from fat, 25% from protein, and only 5% from carbohydrates. Ketosis is a condition where the body does not get enough glucose and instead starts using fat and produces ketones. Ketosis is a completely normal state of the body’s metabolism.
Hello100 company is oriented in production of NMN supplements. NMN is an organic molecule found in all life forms and is a precursor and component for increasing the levels of NAD+ in the organism. NAD+ is an essential coenzyme required for life and cellular functions. Enzymes in our bodies are catalysts that speed up reactions. For instance, digestive enzymes are proteins that break down larger molecules like fats into smaller molecules that are easier to absorb across the intestine. Coenzymes are “helper” molecules that enzymes need in order to function. NAD+ is used by many proteins, such as the sirtuins, which repair damaged DNA. It is also important for mitochondria, which generate the chemical energy that our bodies use. Hello100 creates a liposomal NMN formula in cooperation with scientists. A liposome is a spherical-shaped vesicle that is composed of one or more phospholipid bilayers, which closely resemble the structure of cell membranes. Our body consists of cells. These cells have a membrane, which is made of organic molecules phospholipids. The ability of liposomes to encapsulate drugs inside them has allowed these vesicles to become useful drug delivery systems. The liposomal form of nicotinamide mononucleotide offers faster and more stable delivery of NMN into cells because these artificial vesicles with drugs can easily merge with cell membranes. Another reason why Hello100 company’s NMN supplements work so well is that these supplements have a list of very effective supporting ingredients including betaine, vitamin B12, resveratrol, and folate, which help increase NAD levels and activate longevity genes.
Eternans is a UK biotechnology company and longevity startup, developing senolytic agents for the treatment of senescence-associated diseases. The concept of senolytic therapy is that apoptosis can be selectively initiated in senescent cells. Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells. In adults, apoptosis is used to rid the body of cells that have been damaged during cell division in repairing processes.
Centaura is a young, global team of ambitious people who have the main purpose to slow down aging processes. Company is in Switzerland. As mentioned above, the medical advances of the last few decades may have extended life expectancy, but do not increase the maximum of human’s life expectancy. But Swiss scientists’ company has an ambitious mission – use gene therapy to slow down aging processes or maybe even overcome the naturally existing lifespan barrier. The scientists are creating the Human Artificial Chromosome or HAC. The process is long-lasting and requires a lot of time and resources, but it could bring an amazing result in the future.
Norwegian scientist’s company has a deep understanding in aging, genetics and predictive analytics. We collaborate closely with world-leading experts on building prediction algorithms based on epigenetics. Epigenetics is a branch of genetic science. Genetics has explained how our heredity occurs, revealing the causes of some diseases. Still, a number of uncertainties remain, such as mental illness: some of them do not cause any genetic alterations or anomalies. So, epigenetics does not explain everything at the gene and DNA molecular level. It is a much more flexible and sophisticated science about the modifications of DNA and the proteins surrounding a DNA molecule. In other words, science of epigenetics can explain the mechanisms of transmission of environmental effects. Epigenetics is a new area of science as well as this Agelabs team, but the opportunities and abilities of this research could be an effective tool in treatment of illnesses related to aging processes.